GMS 8.2 includes improvements to the MODPATH model interface. The biggest change is that GMS saves the MODPATH files with the project, and reads the pathline solutions when reading the project. This is especially helpful for transient MODFLOW models with large grids where MODPATH can take a considerable amount of time to run. The option to run MODPATH automatically now only works for steady state models. This option is available by selecting "General Options" in the MODPATH menu. The toggle is near the bottom of the dialog.
A second added feature for GMS 8.2 is that MODPATH pathlines can now be converted to a coverage. This is available by selecting "Pathlines -> Arcs" from the MODPATH menu.
Another feature that will be coming in GMS 8.3 is that MODPATH pathline colors can be set based on the MODPATH zone code for the grid cell the path line is crossing. An example is shown in the screenshot below. For this model, each grid layer has a different MODPATH zone code, so the pathlines change color as they pass through different layers. This option will be available by selecting Display Options from the MODPATH menu and then selecting "Cell zone code" from the color popup menu.